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M9480536.TXT
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1994-08-20
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Document 0536
DOCN M9480536
TI Epidemic of herpes zoster following HIV epidemic in Manipur, India.
DT 9410
AU Panda S; Sarkar S; Mandal BK; Singh TB; Singh KL; Mitra DK; Sarkar K;
Tripathy SP; Deb BC; ICMR Unit for Research on AIDS in north eastern
states of India,; Calcutta.
SO J Infect. 1994 Mar;28(2):167-73. Unique Identifier : AIDSLINE
MED/94308574
AB Since 1989, injecting drug use (IDU) related HIV infection has affected
thousands of young adults in Manipur, a north eastern state of India
bordering Myanmar following a similar kind of epidemic in adjoining
countries like Thailand and Myanmar. During a clinical surveillance of a
group of HIV positive IDUs for a natural history study at Manipur,
herpes zoster (HZ) emerged as the most specific early HIV related
illness (positive predictive value of 100%) in patients belonging to the
age group of 12-45 years. Data collected from the dermatology
departments of the two main hospitals of the state revealed that there
had been an epidemic of HZ since 1990 (rate of 1990 being 11.3/1000
compared to 6.5/1000 in 1989, P value < 0.0001) among males of 12-45
years. The epidemic of HZ has been attributed to the preceding epidemic
of IDU related HIV in the same age and gender group occurring 1 year
earlier. HZ should be recognised as a marker condition similar to
tuberculosis indicating the necessity of screening for HIV in regions
where the dual problem of IDU and HIV exist in young adults.
DE Adolescence Adult Age Factors AIDS-Related Opportunistic
Infections/*EPIDEMIOLOGY Child Comparative Study *Disease Outbreaks
Female Herpes Zoster/*EPIDEMIOLOGY Human HIV Infections/*EPIDEMIOLOGY
India/EPIDEMIOLOGY Male Middle Age Predictive Value of Tests Risk
Factors *Substance Abuse, Intravenous JOURNAL ARTICLE
SOURCE: National Library of Medicine. NOTICE: This material may be
protected by Copyright Law (Title 17, U.S.Code).